Editorial

Acknowledgment to reviewers of Extracellular Vesicles and Circulating Nucleic Acids in 2024

EVCNA Editorial Office

Extracell Vesicles Circ Nucleic Acids. 2025;6:33-5. DOI: 10.20517/evcna.2025.05

Editorial | Available online: 7 Feb 2025

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Review

Consistency in bacterial extracellular vesicle production: key to their application in human health

Ke Dai, ... Qiong Liu

Extracell Vesicles Circ Nucleic Acids. 2025;6:1-20. DOI: 10.20517/evcna.2024.76

Review | Available online: 16 Jan 2025

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Extracellular vesicles and miRNA-based therapies in triple-negative breast cancer: advances and clinical perspectives

Caroline Patini de Rezende, ... Debora Aparecida Pires de Campos Zuccari

Extracell Vesicles Circ Nucleic Acids. 2025;6:54-71. DOI: 10.20517/evcna.2024.85

Review | Available online: 13 Feb 2025

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Extracellular vesicle-mediated chemoresistance in breast cancer: focus on miRNA cargo

Maria Chiara Ciferri, Roberta Tasso

Extracell Vesicles Circ Nucleic Acids. 2025;6:112-27. DOI: 10.20517/evcna.2024.90

Review | Available online: 23 Feb 2025

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The times they are AI-changing: AI-powered advances in the application of extracellular vesicles to liquid biopsy in breast cancer

Vanesa García-Barberán, ... Alberto Benito-Martin

Extracell Vesicles Circ Nucleic Acids. 2025;6:128-40. DOI: 10.20517/evcna.2024.51

Review | Available online: 27 Feb 2025

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Extracellular vesicles: emerging therapeutic agents for liver fibrosis

Giulia Chiabotto, ... Stefania Bruno

Extracell Vesicles Circ Nucleic Acids. 2025;6:216-44. DOI: 10.20517/evcna.2025.08

Review | Available online: 6 May 2025

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Therapeutic potential of extracellular vesicles for treating human pregnancy disorders

Shixuan Zheng, ... Bill Kalionis

Extracell Vesicles Circ Nucleic Acids. 2025;6:287-309. DOI: 10.20517/evcna.2025.07

Review | Available online: 11 Jun 2025

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Extracellular vesicles: cargo loading, degradation and secretory pathways, and their intersection with autophagy

Jinzhe Ju, ... Kasper M.A. Rouschop

Extracell Vesicles Circ Nucleic Acids. 2025;6:360-85. DOI: 10.20517/evcna.2025.21

Review | Available online: 15 Jul 2025

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Exosome miRNA sorting controlled by RNA-binding protein-motif interactions

Zixuan Huang, ... Gaofeng Liang

Extracell Vesicles Circ Nucleic Acids. 2025;6:475-503. DOI: 10.20517/evcna.2025.47

Review | Available online: 10 Aug 2025

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Harnessing artificial intelligence for engineering extracellular vesicles

Hui Lu, ... Jiacan Su

Extracell Vesicles Circ Nucleic Acids. 2025;6:522-46. DOI: 10.20517/evcna.2025.35

Review | Available online: 1 Sep 2025

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Microfluidic devices for on-chip quantification of extracellular vesicles and associated biomarkers

Víctor Calero, ... Esther Serrano-Pertierra

Extracell Vesicles Circ Nucleic Acids. 2025;6:560-79. DOI: 10.20517/evcna.2025.10

Review | Available online: 11 Sep 2025

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Beyond preclinical promise: can mesenchymal stromal cell-derived extracellular vesicles reliably target tubular epithelial cells?

Linrong Pan, ... Marcella Franquesa

Extracell Vesicles Circ Nucleic Acids. 2025;6:580-93. DOI: 10.20517/evcna.2025.54

Review | Available online: 22 Sep 2025

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Tear-derived extracellular vesicles as diagnostic biomarkers for ocular and neurodegenerative diseases: opportunities and challenges

Marta Sanroque-Muñoz, ... Francesc E. Borràs

Extracell Vesicles Circ Nucleic Acids. 2025;6:609-25. DOI: 10.20517/evcna.2025.72

Review | Available online: 29 Sep 2025

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Stem-cell-derived extracellular vesicles in neurodegeneration and neuroaging: therapeutic potential and challenges

Mohit Kumar, ... Susmita Sil

Extracell Vesicles Circ Nucleic Acids.. 2025;6:594-608. DOI: 10.20517/evcna.2025.65

Review | Available online: 29 Sep 2025

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Original Article

Disease-specific signatures of circulating extracellular vesicles detected by the surface plasmon resonance imaging: a pilot study

Tatsuki Shibuta, ... Tsukuru Umemura

Extracell Vesicles Circ Nucleic Acids. 2025;6:36-53. DOI: 10.20517/evcna.2024.82

Original Article | Available online: 10 Feb 2025

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Rapid in situ mutation detection in extracellular vesicle DNA

Md Mofizur Rahman, ... Yuan Wan

Extracell Vesicles Circ Nucleic Acids. 2025;6:72-86. DOI: 10.20517/evcna.2024.69

Original Article | Available online: 16 Feb 2025

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IFNγ preconditioning improves neuroprotection of MSC-derived vesicles on injured retinal ganglion cells by suppressing microglia activation via miRNA-dependent ribosome activity

Tianjing You, ... Xiang Ma

Extracell Vesicles Circ Nucleic Acids. 2025;6:87-111. DOI: 10.20517/evcna.2024.66

Original Article | Available online: 18 Feb 2025

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Impact of exosomes derived from adipose stem cells on lymphocyte proliferation and phenotype in mouse skin grafts

Xinqiang Li, ... Dahong Teng

Extracell Vesicles Circ Nucleic Acids. 2025;6:141-57. DOI: 10.20517/evcna.2024.52

Original Article | Available online: 6 Mar 2025

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Secretome and extracellular vesicle signatures in bone marrow-derived mesenchymal stromal cells after expansion in standard and next-generation media

Giulio Grieco, ... Laura de Girolamo

Extracell Vesicles Circ Nucleic Acids. 2025;6:195-215. DOI: 10.20517/evcna.2024.99

Original Article | Available online: 28 Apr 2025

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Tumor microenvironment: new era in exosomal circRNA research - a bibliometric analysis

Hai-Quan Wang, ... Gang Chen

Extracell Vesicles Circ Nucleic Acids. 2025;6:245-66. DOI: 10.20517/evcna.2024.102

Original Article | Available online: 18 May 2025

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Bovine milk extracellular vesicles prepared by ultracentrifugation contain microbial mRNAs that do not accumulate in human plasma following milk consumption

Peerzada T. Mumtaz, ... Janos Zempleni

Extracell Vesicles Circ Nucleic Acids. 2025;6:276-86. DOI: 10.20517/evcna.2024.84

Original Article | Available online: 28 May 2025

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Optimized size exclusion chromatography demonstrates that extracellular vesicles are the key RNA carriers of ALK translocations in non-small cell lung cancer cell line secretome and patient plasma

Beatriz Benayas, ... María Yáñez-Mó

Extracell Vesicles Circ Nucleic Acids. 2025;6:310-23. DOI: 10.20517/evcna.2025.14

Original Article | Available online: 17 Jun 2025

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CD9+ and CD82+ extracellular vesicles in synovial fluid differentiate aseptic from septic endoprosthesis loosening

Tobias Tertel, ... Bernd Giebel

Extracell Vesicles Circ Nucleic Acids. 2025;6:336-49. DOI: 10.20517/evcna.2025.11

Original Article | Available online: 9 Jul 2025

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Overproduction of β-barrel outer membrane proteins in Escherichia coli BL21(DE3) induces hypervesiculation

Saloni Sahu, ... Peter van Ulsen

Extracell Vesicles Circ Nucleic Acids. 2025;6:386-402. DOI: 10.20517/evcna.2025.27

Original Article | Available online: 16 Jul 2025

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Preanalytical framework for routine clinical use of liquid biopsies: combining EVs and cfDNA

Nike K. Simon, ... Katharina Clemm von Hohenberg

Extracell Vesicles Circ Nucleic Acids.. 2025;6:626-50. DOI: 10.20517/evcna.2025.44

Original Article | Available online: 8 Oct 2025

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Conference Report

A report on the global conference on research and application of Chinese herbal medicine-derived extracellular vesicle-like particles (2024): utilizing medicinal plant-derived extracellular vesicles to advance global pharmaceutical development

Yingqi Cao, ... Kewei Zhao

Extracell Vesicles Circ Nucleic Acids. 2025;6:21-32. DOI: 10.20517/evcna.2024.98

Conference Report | Available online: 17 Jan 2025

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A comprehensive summary of the GISM annual meeting 2025

Enrico Ragni, ... Luisa Pascucci

Extracell Vesicles Circ Nucleic Acids. 2025;6:504-15. DOI: 10.20517/evcna.2025.61

Conference Report | Available online: 13 Aug 2025

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UKEV forum 2024: The UK Society for Extracellular Vesicle annual meeting - bridging innovation and impact

Hannah K. Jackson, ... Charlotte Lawson

Extracell Vesicles Circ Nucleic Acids. 2025;6:516-21. DOI: 10.20517/evcna.2025.62

Conference Report | Available online: 20 Aug 2025

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The 4th annual American Society for Intercellular Communication (ASIC) meeting, 2024 conference report

Ashley E. Russell, ... Aurelio Lorico

Extracell Vesicles Circ Nucleic Acids. 2025;6:547-59. DOI: 10.20517/evcna.2025.51

Conference Report | Available online: 2 Sep 2025

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Commentary

Gas-powered extracellular vesicles promote bone regeneration

Lexie Shannon Holliday, ... Xianrui Yang

Extracell Vesicles Circ Nucleic Acids. 2025;6:158-65. DOI: 10.20517/evcna.2024.91

Commentary | Available online: 18 Mar 2025

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CD63, a new therapeutical candidate for cholesterol homeostasis regulation through extracellular vesicles?

Julien Saint-Pol, Laurence Fenart

Extracell Vesicles Circ Nucleic Acids. 2025;6:166-70. DOI: 10.20517/evcna.2024.92

Commentary | Available online: 18 Mar 2025

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Unraveling the role of amphisomes in mast cell secretory granule fusion and exosome release

Irene Tsilioni

Extracell Vesicles Circ Nucleic Acids. 2025;6:176-9. DOI: 10.20517/evcna.2024.96

Commentary | Available online: 23 Mar 2025

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A milestone for the therapeutic EV field: FDA approves Ryoncil, an allogeneic bone marrow-derived mesenchymal stromal cell therapy

Bernd Giebel

Extracell Vesicles Circ Nucleic Acids. 2025;6:183-90. DOI: 10.20517/evcna.2025.02

Commentary | Available online: 24 Mar 2025

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A new hope for pulmonary hypoplasia: amniotic fluid stem cell extracellular vesicles?

Ishara Atukorala, ... Lisa Hui

Extracell Vesicles Circ Nucleic Acids. 2025;6:350-4. DOI: 10.20517/evcna.2025.25

Commentary | Available online: 9 Jul 2025

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Research Highlight

Inhalable exosomes to target cardiac repair

Ajit Magadum

Extracell Vesicles Circ Nucleic Acids. 2025;6:180-2. DOI: 10.20517/evcna.2024.81

Research Highlight | Available online: 24 Mar 2025

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Sustained release of cytokines from migrasomes

Yan Zhen, ... Harald Stenmark

Extracell Vesicles Circ Nucleic Acids. 2025;6:171-5. DOI: 10.20517/evcna.2025.15

Research Highlight | Available online: 19 Mar 2025

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Exosomal miR-302b as a novel strategy for reversing cellular senescence and promoting healthy aging

Consuelo Borrás

Extracell Vesicles Circ Nucleic Acids. 2025;6:191-4. DOI: 10.20517/evcna.2025.24

Research Highlight | Available online: 1 Apr 2025

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The role of plant extracellular vesicles in cell wall remodeling

Carine de Marcos Lousa

Extracell Vesicles Circ Nucleic Acids. 2025;6:267-71. DOI: 10.20517/evcna.2025.17

Research Highlight | Available online: 27 May 2025

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Small extracellular vesicles, their cargo, and oxidative stress: emerging biomarkers for glaucoma diagnosis and treatment

Francisco J. Romero, ... Manuel Diaz-Llopis

Extracell Vesicles Circ Nucleic Acids. 2025;6:272-5. DOI: 10.20517/evcna.2025.22

Research Highlight | Available online: 27 May 2025

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From gains to liver pain: when exercise training goes too far

Benjamin I. Burke, ... Ahmed Ismaeel

Extracell Vesicles Circ Nucleic Acids. 2025;6:324-7. DOI: 10.20517/evcna.2025.36

Research Highlight | Available online: 24 Jun 2025

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Blebbisomes as autonomous communication hubs

Ying Gao, ... Tiebang Kang

Extracell Vesicles Circ Nucleic Acids. 2025;6:355-9. DOI: 10.20517/evcna.2025.38

Research Highlight | Available online: 10 Jul 2025

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Letter to Editor

Reproducibility and transparency: why following MISEV guidelines is beneficial for the studies on EVs and brain barriers

Julien Saint-Pol

Extracell Vesicles Circ Nucleic Acids. 2025;6:328-35. DOI: 10.20517/evcna.2024.63

Letter to Editor | Available online: 2 Jul 2025

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Systematic Review

Extracellular vesicles as vehicles for small non-coding RNA therapeutics: standardization challenges for clinical translation

Lucrezia Luisotti, ... Claudia Martini

Extracell Vesicles Circ Nucleic Acids. 2025;6:403-32. DOI: 10.20517/evcna.2025.33

Systematic Review | Available online: 31 Jul 2025

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Meeting Abstracts

Meeting abstracts of the GISM Annual Meeting 2025

Enrico Ragni, ... Michela Pozzobon

Extracell Vesicles Circ Nucleic Acids. 2025;6:433-74. DOI: 10.20517/evcna.2025.53

Meeting Abstracts | Available online: 3 Aug 2025

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