2025 Annual Report of Rare Disease and Orphan Drugs Journal
The year 2025 marked a solid stage in the development of Rare Disease and Orphan Drugs Journal (RDODJ; ISSN 2771-2893), with continued growth in manuscript submissions, publications, and international engagement. During the year, the journal further strengthened its editorial standards, broadened its global author base, and enhanced its visibility within the rare disease research community.
Highlights
- Indexing and metrics: Indexed in Scopus (May 2025) and the Emerging Sources Citation Index (ESCI; September 2025), with all articles now included in the Web of Science. Expected to receive its first Impact Factor in June 2026.
- Submissions and publications: Received 89 submissions and published 35 peer-reviewed articles.
- Rejection rate: Increased from 48.39% in 2024 to 66.67% in 2025, reflecting stricter editorial screening and quality control.
- Article types: Reviews (54%) and Original Articles (29%) together accounted for 83% of published content.
- Author distribution: Published articles included authors from 15 countries, led by the United States (22%), Japan (16%), and China, Italy, and the Netherlands (11% each), reflecting broad international participation across North America, Europe, and Asia.
- Citations: Articles published in RDODJ received 131 citations in 2025, representing a 49% increase compared with 2024 (88 citations).
- Special Issues: Published 4 Special Issues covering Kallmann syndrome, neurodevelopmental disorders, multi-omics insights, and translational research from animal models to clinical practice.
- Editorial Board updates: 13 new members joined the Editorial Board, including 2 Associate Editors, 9 Editorial Board Members, and 2 Youth Editorial Board Members. The Board now comprises 49 members from 14 countries/regions.
- Expert interviews: Conducted interviews with 8 researchers from leading institutions in China, Europe, Australia, and the United States.
- Editorial Board meeting: Held 1 Editorial Board meeting in October 2025, chaired by the Editor-in-Chief, Prof. Daniel Scherman.
1. Indexing and Databases
In 2025, RDODJ achieved indexing in Scopus and the Emerging Sources Citation Index (ESCI), marking an important step in the journal's development. All published articles are now included in the Web of Science. The journal is expected to receive its first Impact Factor in June 2026.
2. Submissions and Publications
Figure 1. Submissions and Publications (2021-2025)
From 2021 to 2025, RDODJ experienced a steady increase in both submissions and publications. Annual submissions rose from 5 in 2021 to 89 in 2025, while published articles increased from 5 to 35 over the same period, reflecting enhanced journal visibility and author confidence.
Figure 2. Rejection Rate (2021-2025)
The rejection rate increased progressively from 0% in 2021 to 66.67% in 2025, indicating the journal's continued efforts to apply rigorous peer review and maintain high academic standards.
Figure 3. Article Type Distribution (2021-2025)
Across five years, RDODJ published a diverse range of article types, including Reviews (46%), Original Articles (17%), and Perspectives (13%), complemented by Editorials, Case Reports, Opinions, and other formats.
Figure 4. Article Type Distribution (2025)
In 2025, Reviews (54%) and Original Articles (29%) constituted the majority of published content, underscoring the journal's focus on comprehensive syntheses and original research contributions.
Figure 5. Country Distribution of Authors
Authors originated from 15 countries, with the largest contributions from the United States (22%), Japan (16%), and China, Italy, and the Netherlands (11% each), highlighting RDODJ's international author base.
3. Citations and Readership
Figure 6. Citations (2021-2025, Google Scholar)
The journal's citations have shown steady and significant growth over the past five years. Starting from just 1 citation in 2021, the number increased to 6 in 2022, 24 in 2023, 86 in 2024, and reached 131 in 2025, reflecting the journal's increasing academic impact and visibility in the field.
Table 1. Top 10 Most-Read Articles in 2025
The ten most-read articles in 2025 covered topics including neurodevelopmental disorders, genetic therapies, and diagnostics. Article views ranged from 576 to 1,159, with the most-read article focused on Duchenne muscular dystrophy.
4. Special Issues
In 2025, RDODJ published four Special Issues addressing focused and emerging topics in rare disease research. These collections were curated by internationally recognized Guest Editors and attracted strong community interest.
Table 2. Special Issues Published in 2025
| Cover | Topic | Guest Editors |
|---|---|---|
 | Advances in the Diagnosis, Management, and Therapeutics of Kallmann Syndrome with Insights into Genetic Etiology | Prof. Jihong Liu, Prof. Hao Xu |
 | Rare Neurodevelopmental Disorders: From Genetics to Evidence-Based Clinical Management | Dr. Martina Siracusano |
 | Genomic and integrated multi-omics Insights into Rare Genetic Diseases: From Discovery to Clinical Translation | Prof. Juergen Reichardt |
 | Clinical Translation of Findings from Rare Disease Animal Models to Veterinary Patients: Practical Reality or Elusive Dream | Prof. Joe Kornegay |
5. Editorial Board Updates
In 2025, RDODJ expanded its Editorial Board by welcoming 13 new members, including 2 Associate Editors, 9 Editorial Board Members, and 2 Youth Editorial Board Members. The Board now consists of 49 experts from 14 countries/regions, with the largest representation from China, France, and the United States.
Table 3. Associate Editors and Editorial Board Members Appointed in 2025
| Photo | Name | Position | Institution |
|---|---|---|---|
 | Phillip D.K. Lee | Associate Editor | University of Texas Medical Branch, Galveston, TX, USA |
 | Neal J. Weinreb | Associate Editor | University of Miami School of Medicine, Boca Raton, USA |
 | Richard H. Finnell | Editorial Board Member | Baylor College of Medicine, Houston, USA |
 | Bin Lu | Editorial Board Member | University of South China, Hengyang, Hunan, China |
 | Franz Schaefer | Editorial Board Member | University Hospital Heidelberg, Heidelberg, Germany |
 | Xiaoping Luo | Editorial Board Member | Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China |
 | Ke Wu | Editorial Board Member | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China |
 | Jihong Liu | Editorial Board Member | Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China |
 | Jinxiang Han | Editorial Board Member | Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China |
 | Kees Noordam | Editorial Board Member | Radboud University Medical Centre, Nijmegen, the Netherlands |
 | Juergen Reichardt | Editorial Board Member | James Cook University, Cairns, Australia |
 | Jingying Wu | Youth Editorial Board Member | Shanghai Sixth People's Hospital, Shanghai, China |
 | Quanjun Yang | Youth Editorial Board Member | Shanghai Sixth People's Hospital, Shanghai, China |
Figure 7. Distribution of Editorial Board Members by Country/Region
6. Expert Interviews
In 2025, RDODJ conducted expert interviews with eight researchers from leading institutions, including universities and research networks in China, Italy, Greece, Australia, France, the United Kingdom, Ibero-America, and the United States. These interviews promoted scholarly exchange and provided perspectives on emerging research trends.
Figure 8. Expert Interviews in 2025
7. Editorial Board Meeting
Under the leadership of Editor-in-Chief Prof. Daniel Scherman, RDODJ successfully held an Editorial Board meeting in October 2025. Board members reviewed journal performance, discussed editorial policies, and exchanged views on future development strategies.
Figure 9. Online Editorial Board Meeting in 2025
Acknowledgments
Overall, 2025 represents a year of steady progress for RDODJ. With improved editorial selectivity, expanded international participation, growing citation activity, and enhanced indexing coverage, RDODJ continues to develop as a credible platform for rare disease research. We sincerely thank all Editorial Board members, authors, reviewers, readers, and editorial staff for their contributions and look forward to further strengthening the journal's academic contribution in the years ahead.
Editor: Alani Luo
Editor: Monica
Language Editor: Catherine Yang
Production Editor: Ting Xu
Respectfully Submitted by the Editorial Office of Rare Disease and Orphan Drugs Journal
