fig3

Figure 3. GO and KEGG enrichment analyses of upregulated and downregulated DEGs following ITGB5 overexpression. (A) GO enrichment bubble plot for upregulated DEGs; (B) KEGG enrichment bubble plot for upregulated DEGs; (C) GO enrichment bubble plot for downregulated DEGs; (D) KEGG enrichment bubble plot for downregulated DEGs. DEGs: Differentially expressed genes; DETs: differentially expressed transcripts; GO: gene ontology; KEGG: kyoto encyclopedia of genes and genomes; VEGF: vascular endothelial growth factor; EGFR: epidermal growth factor receptor; TAP: transporter associated with antigen processing; ABC: ATP-binding cassette; MHC: major histocompatibility complex; NFAT: nuclear factor of activated T cells.