fig1

Figure 1. Expression of m³C-related molecules in HCC and their effects on HCC cell lines. (A) Relative mRNA expression levels of six m³C regulators in 16 pairs of HCC and adjacent tissues measured by qRT-PCR; (B) CCK8 assay assessing HCC cell proliferation following m³C regulator knockdown or overexpression; (C) Wound healing assay evaluating changes in cell migration ability after overexpression or downregulation of m³C regulators. (**** P < 0.0001, *** P <0.001, ** P <0.01, * P < 0.05, ns: not significant, P > 0.05). HCC: Hepatocellular carcinoma; m³C: 3-methylcytidine; qRT-PCR: quantitative real-time PCR.