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Figure 8. Immunologic gene set enrichment analysis of CHST14-expressing clusters in STAD_GSE134520. (A) Heatmap of upregulated immunologic gene sets, highlighting enriched pathways such as “Toll-like receptor signaling” and “IL-6/JAK/STAT3 signaling” in CHST14-high clusters (16 and 18). (B) Heatmap of downregulated immunologic gene sets, showing suppression of pathways like “T-cell receptor signaling” and “Antigen presentation via MHC Class II” in CHST14-high clusters.
