Topic: Drug Resistance and Cancer Stem Cell

Solid tumors as well as leukemias and lymphomas depend for their proliferation on a small group of progenitor cells, the cancer stem cells. These are tumorigenic and both self-renew and generate more differentiated, non-tumorigenic cells. The cancer stem cells are responsible for metastases, as well as for the post-therapeutic relapses of tumors. Therefore, there is a great interest and importance in identifying and, if possible, specifically targeting the cancer stem cells. Recent developments in single cell omics approaches hold great promise in this regard.
The Special Issue on "Cancer Stem Cells" will include Original Articles, Reviews, Commentaries, etc. updating the current state of knowledge and clinical uses of identifying and targeting cancer stem cells. The Special Issue will also include Research articles presenting novel outstanding data on all aspects of cancer stem cell-targeted therapies. All submissions will undergo rigorous peer review and will be published free of charge upon acceptance.

Biomarkers, differentiation therapy, metastasis, omics, relapse, single cell studies, stemness

31 Aug 2019