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Figure 5. Biodegradability and biocompatibility of NeuroSyn. (A) Biodegradation of NeuroSyn in vivo over a time frame of 20 weeks; (B) H&E-stained histological sections of heart, liver, spleen, lung, and kidney at 8 weeks post-implantation; (C and D) Analysis of blood chemistry and blood counts of rats at 4 weeks (C) and 8 weeks (D) post-implantation. Data are presented as mean ± SD in (A) to (D), n = 3 animals in each group. NeuroSyn: A biosynchronized, transient and flexible regenerative peripheral neural interface; SD: standard deviation; ALT: aminotransferase; TBIL: total bilirubin; BUN: blood urea nitrogen; CREA: creatinine.