fig6

Figure 6. Wearable plasmonic paperfluidic device for sweat analysis using SERS. (A) Conceptual illustration of the device for sweat collection, transport, and in-situ analysis; (B) Top view and (C) layered schematic showing the encapsulation layer, paperfluidic channels, plasmonic paper, and laser blocker; (D) Image of the fabricated device with six AuNR-based plasmonic sensors; (E) TEM image of AuNRs; (F) Extinction spectra comparing AuNRs in solution and on paper; (G) A portable Raman spectrometer with a flexible fiber probe for spectra collection; (H) SERS spectra of UA (100 μM) at different laser distances before and (I) after normalization; (J) SERS spectra comparison between benchtop and portable spectrometers; (K) Image of the device after human wear during exercise; (L) SERS spectrum from sweat collected at sensor. Reprinted with permission from^[112], Copyright © 2022, The American Association for the Advancement of Science. SERS: Surface-enhanced Raman spectroscopy; AuNR: gold nanorod; TEM: transmission electron microscopy; UA: uric acid.