fig3

Urinary extracellular vesicles detect altered renal circulation in human obesity

Figure 3. Characterization of CD31-/PLVAP+/CD144-/MCP-1+ uEVs in Lean and Obese Individuals. (A) Levels of CD31-/PLVAP+/CD144-/MCP-1+ uEVs fractions were elevated in obese vs. lean individuals, *P < 0.05, t-test; (B-E) Correlations of CD31-/PLVAP+/CD144-/MCP-1+ uEV levels with BMI, MAP, blood glucose, and urinary NGAL, respectively. CD31: Cluster of differentiation 31; PLVAP: plasmalemma vesicle-associated protein; CD144: cluster of differentiation 144; MCP-1: monocyte chemoattractant protein-1; uEV: urinary extracellular vesicle; BMI: body mass index; MAP: mean arterial pressure; NGAL: neutrophil gelatinase-associated lipocalin.

Metabolism and Target Organ Damage
ISSN 2769-6375 (Online)
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