Metabolism and Target Organ Damage (M&TOD) is an international, peer-reviewed, open-access interdisciplinary journal that provides an online platform for the publication of clinical, basic, and translational studies. It covers cardio-metabolic disorders per se, such as obesity, diabetes, dyslipidemias, arterial hypertension, and hyperuricemia in all age groups. Of note, this journal will emphasize the role of these metabolic disorders as either effectors/amplifiers or consequences of the development and progression of injuries to target organs including but not limited to the cardiovascular system, the liver, kidneys, and the pancreas. Specific applications in metabolic disorders are as follows: history of the disease, epidemiology, prevention, natural history, genetics, cell, and molecular biology, pathobiochemistry, physiopathology, anatomic pathology, clinical chemistry, pharmaceutical chemistry, pharmacology, psychology, psychiatry, statistics, and immunology.
From a clinical point of view, the journal covers aspects of biomarkers, diagnosis, prognosis and all types of innovative management strategies including cognitive-behavioral approaches and randomized controlled trials of innovative drug schedules of metabolic disorders. M&TOD welcomes to publish researches to promote the development of animal-free models of studies including cell cultures, artificial intelligence and others.
M&TOD particularly welcomes studies of translational value of ranging from basic science to clinical applications which is interested in evaluating submissions pertaining to all areas of public health including health policy; health economics, internal medicine and its sub-specialties, such as cardiology, endocrinology hepato-gastroenterology, nephrology, oncology, general surgery and its branches such as bariatric, endocrine, vascular, metabolic, oncological surgery.
M&TOD accepts submissions of the following editorial categories: Original Article, Review, Commentary, Mini-Review, Systematic Review, Meta-analysis, Editorial, Perspective, Opinion, Communication, Letter and Research Highlight.
The main areas of interest include the following:
- Artificial intelligence and cardio-metabolic disorders
- Atrial fibrillation
- Autoimmunity
- Bariatric surgery
- Bile Acids
- Cachexia
- Cancer and metabolic disorders
- Cancerogenesis
- Cellular biology and molecular pathways of insulin resistance
- Cholestasis
- Chronic kidney injury owing to cardio-metabolic disorders
- Cytokines, adipokines and hepatokines
- Cognitive-Behavioral approach to cardio-metabolic disorders
- Coronary artery disease
- C-Reactive Protein
- Diabetes phenotypes
- Diabetic foot ulcer
- Diabetic nephropathy
- Diabetic retinopathy
- Disorders of cardiac valves owing tocardio- metabolic disorders
- Disorders of iron metabolism
- Drug-induced cardio-metabolic disorders
- Dyslipidemia
- Endoplasmic reticulum stress and cardio-metabolic diseases
- Endothelial dysfunction
- Energy homeostasis and cardio-metabolic disorders
- Extra-hepatic manifestations of NAFLD
- Failure to thrive
- Fatty pancreas
- Genetic basis of cardio-metabolic disorders
- Geriatrics and cardio-metabolic disorders
- Gut microbiota, virobiota, mycobiota an cardio-metabolic disorders
- Health economics and cardio-metabolic disorders
- Heart failure
- Hereditary hemochromatosis
- History of cardio-metabolic disorders
- Hormone replacement therapy and cardio-metabolic disorders
- Hypertriglyceridemia
- Hypetrigliceridemia
- Hyperuricemia
- Imaging of cardio-metabolic disorders
- Immuno-metabolism
- Infections and cardio-metabolic disorders
- Insulin sensitizers
- Lifestyle and metabolism
- Lysosomal storage disease
- MAFLD-NAFLD debate
- Mechanisms of cell damage in cardio-metabolic disorders
- Metabolic bone disease
- Metabolic derangements in acute and chronic bacterial and viral infections
- Metabolic surgery
- Metabolic actions of Intra-gastric balloon devices
- Metabolic disorders in liver cirrhosis
- Metabolic disorders in pregnancy
- Metabolic disorders in rheumatology
- Metabolic disorders in the transplanted patients
- Metabolically healthy and unhealthy obesity
- Metabolically obese, normal weight
- Metabolic syndrome
- Metabolism and longevity
- Metabolomics
- Metaflammation
- Migration and cardio-metabolic disorders
- Mitochondrial pathobiology and cardio-metabolic disorders
- Myocardial infarction owing to metabolic disorders
- NAFLD secondary to endocrine disorders
- Neonatal metabolic disorders
- Neurodegenerative disorders and metabolism
- Novel anti-diabetic drug agents
- Novel cholesterol-lowering approaches
- Nuclear Receptors
- Nutriceuticals
- Obesity phenotypes: android vs. gynoid
- Occupational medicine and cardio-metabolic disorders
- Oxidative stress and cardio-metabolic disorders
- Pathobiology of stress and cardio-metabolic disorders
- Pathology of metabolic disorders: from anatomic pathology to histo-cytology
- Pediatric cardio-metabolic disorders
- Pharmacotherapy of cardio-metabolic disorders
- Physical exercise as a treatment of cardio-metabolic disorders
- Physiology of metabolism
- Prevention of cardio-metabolic disorders
- Psychology of cardio-metabolic disorders
- Rare metabolic diseases
- Research gaps in cardio-metabolic disorders
- Sarcopenia and cardio-metabolic disorders
- Screening of cardio-metabolic disorders
- Secondary arterial hypertension
- Sex differences in cardio-metabolic disorders
- Smoking and cardio-metabolic disorders
- Statins
- Steatogenesis
- Stroke
- Systemic inflammation, subclinical
- Telomere attrition
- Thyromimetics and cardio-metabolic disorders
- Thrombosis in metabolic disorders
- Variable topography of atherosclerosis: coronary vs. cerebral vs. visceral vs. peripheral
- Vascular surgery in dysmetabolic indivduals
- Weight loss and ageing