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Figure 2. Characterization of CD31^-/PLVAP⁺/CD144^-/DLL4⁺ uEVs in Lean and Obese Individuals. (A) The CD31^-/PLVAP⁺/CD144^-/DLL4⁺ uEVs fractions were elevated in obese vs. lean individuals, *P < 0.05, t-test; (B-E) Correlations between CD31^-/PLVAP⁺/CD144^-/DLL4⁺ uEV levels and BMI, insulin, angiopoietin-2, and VEGF-A, respectively. CD31: Cluster of differentiation 31; PLVAP: plasmalemma vesicle-associated protein; CD144: cluster of differentiation 144; DLL4: delta-like-ligand-4; VEGF-A: vascular endothelial growth factor-A; uEV: urinary extracellular vesicle; BMI: body mass index.