fig2

Figure 2. Score plot of the OPLS-DA model and comparative analysis of lipidomic profiles. (A) Score plot of the OPLS-DA model in the positive mode; (B) Permutation test of the OPLS-DA model in the positive mode; (C) Categories of the 21 lipid classes form a total of 4001 molecular lipids; (D) The top 6 lipid species in the serum from NC, OB, IGT and OD groups. All models were validated with Q2 ≥ 0.5 and permutation tests P ≤ 0.05. PA: Phosphatidic acid; LPG: lysophosphatidylglycerol; ChE: cholesterylester; LPC: lysophosphatidylcholine; PEt: phosphatidylethanol; SM: sphingomyelins; TG: triacylglycerol; PG: phosphatidylglycerol; PC: phosphatidylcholine; LPE: lysophosphatidylethanolamine; PFAA: plasma free amino acids; WE: wax ester; PE: phosphatidylethanolamine; DG: diacylglycerol; PI: phosphatidylinositol; Hex1Cer: hexose ceramide; AcCa: acyl carnitine; Cer: ceramide; MePC: methylated phosphatidylcholine; MG: monoacylglycerol; CL: cardiolipin.