fig4

Alterations in secondary bile acids in adult-onset subclinical hypothyroidism with mild cognitive impairment

Figure 4. ROC curve analysis of differential BAs of HCs, SCH-NC and SCH-MCI groups. (A) The AUC of differential BAs between HCs and SCH-NC; (B) The AUC of differential BAs between HCs and SCH-MCI; (C) The AUC of differential BAs between SCH-NC and SCH-MCI. alloLCA: Allolithocholic acid; CDCA: chenodeoxycholic acid; GCDCA: glycochenodeoxycholic acid; GDCA: glycodeoxycholic acid; HCs: healthy controls; isoLCA: isolithocholic acid; SCH-NC: subclinical hypothyroidism with normal cognition; SCH-MCI: subclinical hypothyroidism with mild cognitive impairment; T4: thyroxine; TCDCA: taurochenodeoxycholic acid; βGCA: 3β-glycocholic acid; 12-oxo-CDCA: 12-oxochenodeoxycholic acid; ROC: receiver operating characteristic; Bas: bile acids; AUC: area under the curve.

Metabolism and Target Organ Damage
ISSN 2769-6375 (Online)
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