fig1

Novel insights into the purinergic P2X7 receptor signaling in obesity and cardiovascular-kidney-metabolic syndrome: a brief overview

Figure 1. P2X7R-caspase 1-IL-1β axis activation, inflammatory cascade, and resulting clinical scenarios in cardiovascular-kidney-metabolic syndrome. (Created in BioRender; Di Vincenzo A, 2025. https://BioRender.com/frz4vwz). MASH: Metabolic-associated steatohepatitis; IL-1β: interleukin-1β.

Metabolism and Target Organ Damage
ISSN 2769-6375 (Online)
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