fig6

Figure 6. Transcriptome analysis of high and low-risk groups in TCGA. (A) Volcano plot of differentially expressed genes. Green indicates downregulated genes, red indicates upregulated genes, and black indicates genes with no significant expression changes; (B) Heatmap of differentially expressed genes; (C) Bubble plot of KEGG enrichment results. The X-axis represents the gene ratio. The Y-axis represents pathway names, with the size of the points representing the number of genes enriched in that pathway. The color indicates the corrected P-value, with smaller P-values closer to red, signifying greater significance. Only the top 20 pathways are shown here; (D) Bar plots of GO enrichment results. Only the top 10 most significant GO terms for BP, CC, and MF are shown. TCGA: The Cancer Genome Atlas; KEGG: Kyoto Encyclopedia of Genes and Genomes; GO: Gene Ontology; BP: biological process; CC: cell component; MF: molecular function.