fig10

Figure 10. Combined PD-0332991 and JQ1 inhibited tumor growth in vivo. (A) Treatment regimens used in the in vivo study; (B) Xenograft tumors harvested from different groups of nude mice; (C) Body weights of mice in each group; (D) Tumor volume changes in response to treatment. Data are presented as mean ± SEM from three independent experiments. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001; ns: not significant. SEM: Standard error of the mean.