fig3
Figure 3. P-gp overexpression confers resistance to treatment with MIRV. Three-day cytotoxicity assays were performed with MIRV as described in the Materials and Methods using the OVCAR8/NCI-ADR-RES pair (left) or the KB 3-1/KB 8-5-11 pair (right). Results from one of two independent experiments are shown. P-gp: P-glycoprotein; MIRV: mirvetuximab soravtansine.









