fig6

Targeting the hypoxia signaling pathway with nanomedicine to reverse immunotherapy resistance

Figure 6. (A) Albumin-templated manganese dioxide nanoparticles loaded with triphenylphosphine-derived metformin via positive and negative adsorption to form a hybrid nanoadjuvant; (B) These nanoparticles synergized with radiotherapy to elicit antitumor immunological memory. **P < 0.01, ***P < 0.001 [reproduced with permission from Yi et al. (2024)[157]. Copyright 2024 John Wiley and Sons].

Cancer Drug Resistance
ISSN 2578-532X (Online)

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