fig9

Cisplatin resistance in head and neck squamous cell carcinoma is linked to DNA damage response and cell cycle arrest transcriptomics rather than poor drug uptake

Figure 9. (A) Kaplan-Meier plots of recurrence-free survival stratified by FANCD2 expression and adjuvant platinum-based chemotherapy indicate that high FANCD2 expression predicts poor survival in patients treated with platinum-based chemotherapy; (B) This adverse effect remained significant after adjustment for clinical stage and tumor localization in multivariate Cox proportional hazard regression. *P < 0.05.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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