fig1

Cisplatin resistance in head and neck squamous cell carcinoma is linked to DNA damage response and cell cycle arrest transcriptomics rather than poor drug uptake

Figure 1. Cytotoxic pharmacodynamics of cisplatin in HNO41 (black) and HNO97 (dark red). (A) Cytotoxic effects of cisplatin as a function of nominal concentrations in the culture medium; (B) Cytotoxic effects of cisplatin normalized to total intracellular platinum concentrations. Data are presented as mean ± SD from four independent biological replicates, each with eight technical replicates. SD: Standard deviation.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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