fig1

Figure 1. THZ2 suppresses GBM cell proliferation, migration, and invasion. (A) IC₅₀ values of THZ2 in four GBM cell lines; (B and C) Effects of different concentrations of THZ2 on proliferation (B) and colony formation (C) in four GBM cell lines; (D and E) Effects of THZ2 (0.25-0.5 μM for 48 h) on migration (D) and invasion (E) in four GBM cell lines. Scale bars: 50 μM. Data are presented as mean ± SD from three independent experiments (n = 3). ns: Not significant, ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. Statistical significance was assessed using one-way ANOVA. GBM: Glioblastoma; SD: standard deviation; ANOVA: analysis of variance.