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From: Two rare cancers of the exocrine pancreas: to treat or not to treat like ductal adenocarcinoma?

Figure 3. Histologic appearance of PACC. H&E specimens of PACC. (A) Low power image showing how PACC recapitulates the architecture of the exocrine pancreatic parenchyma with back-to-back acinar structures containing lumina. The tumor clusters are irregular in size and shape and are approaching the peri- pancreatic adipose tissue (40×). (B) Higher power image showing the classic cytologic features of PACC with basally located nuclei containing single prominent nucleoli, and abundant apical amphophilic and granular cytoplasm (400×).