Special Issue
Topic: Advances in DNA Damage & Repair and Cancer Drug Resistance
Guest Editor(s)
Dr. Eddy S. Yang
Hazelrig Salter Radiation Oncology Center, 1700 6th Avenue South Birmingham, AL, USA.
Special Issue Introduction
With the recent clinical successes of the PARP inhibitors, the DNA repair pathways have come to the forefront as a bona fide target for personalized treatment of cancers with defective homologous recombination repair. Additionally, DNA repair (genome instability) is a well-established hallmark of cancer and can be a means for dictating tumor sensitivity and resistance to traditional treatments such as chemotherapy and radiation. In this Special Issue, we will provide a basic, translational, and clinical overview of the interactions of the various DNA repair pathways as it relates to carcinogenesis, treatment, and biomarker of response.
Keywords
DNA damage response pathways, DNA repair pathways, cellular response to chemotherapeutics, DNA damage response/repair inhibitors, combination therapy, genome instability, immunotherapy
Submission Deadline
31 Aug 2020
Submission Information
For Author Instructions, please refer to https://www.oaepublish.com/cdr/author_instructions
For Online Submission, please login at https://oaemesas.com/login?JournalId=cdr&SpecialIssueId=380
Submission Deadline: 31 Aug 2020
Contacts: Susan Song, Assistant Editor, susan@cdrjournal.com
Published Articles
Targeting DNA repair pathways to overcome cancer drug resistance
Open Access Editorial 18 Aug 2021
DOI: 10.20517/cdr.2021.80
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DNA direct reversal repair and alkylating agent drug resistance
Open Access Review 18 Jun 2021
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Exploiting DNA repair pathways for tumor sensitization, mitigation of resistance, and normal tissue protection in radiotherapy
Open Access Review 18 Jun 2021
DOI: 10.20517/cdr.2020.89
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Resistance to venetoclax and hypomethylating agents in acute myeloid leukemia
Open Access Review 18 Mar 2021
DOI: 10.20517/cdr.2020.95
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Aberrant DNA repair as a potential contributor for the clonal evolution in subsets of anaplastic thyroid carcinomas arising through dedifferentiation: implications for future therapeutic algorithms?
Open Access Commentary 2 Nov 2020
DOI: 10.20517/cdr.2020.66
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Radiotherapy and the cellular DNA damage response: current and future perspectives on head and neck cancer treatment
Open Access Review 16 Sep 2020
DOI: 10.20517/cdr.2020.49
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