fig2

Figure 2. Biocompatibility assay of LMNPs. (A) Cellular level. (i) Survival under different nanomaterials in culture^[114], ^*symbols indicate all cells died; (ii) Survival of MCF-7 cells cultured at different concentrations of molecularly grafted LMNPs^[115]; (B) Tissue level. Histological characterization of impact of LMNPs to major organs^[116]; (C) Organ level. Liver function indicators in mice after injection of 45 mg·kg^-1 LMNPs^[117]. (i) ALT, ALP, and AST levels; (ii) albumin concentrations; and (iii) BUN measured at different times in LM-NP/L blood; (D) Biological level. (i) Survival of mice injected with LMNPs over time^[114]; (ii) Determination of gallium in stool and urine of mice after injection of LMNPs^[117]; (iii) Changes in body weight of mice after injection of different types of LMNPs^[116]. ALP: Alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; bPEG: brushed polyethylene glycol; BUN: blood urea nitrogen; LM: liquid metal; LMNPs: LM nanoparticles; MWCNT: multi-walled carbon nanotube; OA: oleic acid; PMVEMA: poly methyl vinyl ether-alt-maleic anhydride; PSMA: poly styrene-co-maleic anhydride.