fig7

From: The expression characteristics of LBP in spinal tuberculosis and its regulatory effect on the TLR4/NF-κB inflammatory pathway

Figure 7. Under BCG infection conditions, the impact of the NF-κB signaling pathway on the expression of inflammatory cytokine proteins. (A-F) The protein expression levels of MyD88, NLRP3, Caspase-1, CCL3, and IL-1β under BCG infection and Si-LBP interference conditions are presented. All data are presented as mean ± standard deviation. ns (P > 0.05), * (P < 0.05), *** (P < 0.001), n = 3. BCG: Bacillus Calmette-Guérin; SiRNA: small interfering RNA; MyD88: myeloid differentiation primary response 88; NLRP3: NLR family pyrin domain containing 3; CCL3: C-C motif chemokine ligand; IL-1β: interleukin-1β; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; LBP: lipopolysaccharide-binding protein.