REFERENCES

1. Zeng LF, Pan BQ, Liang GH, et al. Does routine anti-osteoporosis medication lower the risk of fractures in male subjects? An updated systematic review with meta-analysis of clinical trials. Front Pharmacol 2019;10:882.

2. Zeng LF. Editorial: The potential effects and mechanisms of Chinese traditional medicine on bone homeostasis and remodeling, volume II. Front Endocrinol 2023;14:1158042.

3. Zhao Z, Cai Z, Chen A, Cai M, Yang K. Application of metabolomics in osteoporosis research. Front Endocrinol 2022;13:993253.

4. Xia TS. Metabolomics study of antiglucocorticoid-induced osteoporosis in Morindae Officinalis Radix and Prepared rhizome of Adhesive Rehmannia. PLA Navy Medical University; 2019 (in Chinese). Available from: https://kns.cnki.net/kcms2/article/abstract?v=lVku9qtM8H-4QGPWbql1lo2IwoqzvLXPJtPE7E2FE2bbYRKWGKNe7HeTQSz8ML-hJFbtg4UPzsETejEjM5K7u7u_5BvajyHEE1SdoTLUlBwaffjZ3D-7ZSc1ebWSxQ2srx397KDx_WnrHt0HjuRkbw==&uniplatform=NZKPT&language=CHS [Last accessed on 30 Nov 2023].

5. Pan S, Chen A, Han Z, Wang Y, Lu X, Yang Y. ¹H NMR-based metabonomic study on the effects of Epimedium on glucocorticoid-induced osteoporosis. J Chromatogr B Analyt Technol Biomed Life Sci 2016;1038:118-26.

6. Wang FJ, Wang T, Luo FM, Zhang CX, Liu S. Study on anti-osteoporosis effect of Eucommiae Cortex based on GC-MS metabonomics. Zhongguo Zhong Yao Za Zhi 2020;45:5555-60.

7. Huang Y, Liu X, Zhao L, Li F, Xiong Z. Kidney tissue targeted metabolic profiling of glucocorticoid-induced osteoporosis and the proposed therapeutic effects of Rhizoma Drynariae studied using UHPLC/MS/MS. Biomed Chromatogr 2014;28:878-84.

8. Jiang YC, Li YF, Zhou L, Zhang DP. UPLC-MS metabolomics method provides valuable insights into the effect and underlying mechanisms of Rhizoma Drynariae protecting osteoporosis. J Chromatogr B Analyt Technol Biomed Life Sci 2020;1152:122262.

9. Li C. Study on anti-osteoporosis mechanism of Shen-Ling Jian-Gu Capsule based on metabonomics. Hebei Medical University; 2017 (in Chinese). Available from: https://kns.cnki.net/kcms2/article/abstract?v=lVku9qtM8H8IvNiLGFNbKa1o9rzO-LljuwtRmSvLMVM5sYn55p9oLlvEqLwzbtV9nnN68xb3YKh2lcbWw-47JiTw0IQKpYlx2mNU6Mb7YgFop0QZNSMrL3nxXMBSukjT26QR4YbIW-mzURgYx7Wl1Q==&uniplatform=NZKPT&language=CHS [Last accessed on 30 Nov 2023].

10. Luo D, Li J, Chen K, Rong X, Guo J. Untargeted metabolomics reveals the protective effect of Fufang Zhenshu Tiaozhi (FTZ) on aging-induced osteoporosis in mice. Front Pharmacol 2018;9:1483.

11. Wu F. Study on metabonomics of Shu-Gan Bu-Shen Formula in treating osteoporosis. Zhejiang Chinese Medicine University; 2016 (in Chinese). Available from: https://kns.cnki.net/kcms2/article/abstract?v=lVku9qtM8H9eqE28el0MrFPUFs01dn2MbWz3jOswEKaYUgGFhMZNAyXwKqyEjzUbeKlDc-mQs0Nw7aukORBqCYDJ38xQzTSI8Psg1RQJRtx-VrFaca1dIiT90Mm6uYnYXYfU6W06ckV5xLrbdAhOOQ==&uniplatform=NZKPT&language=CHS [Last accessed on 30 Nov 2023].

12. Liu WJ, Yang J, Huang MY, Zhang CT, Sun P, Huang YM. Serum metabolomics study of Jian-Gu Granule against osteoporosis in ovariectomized rats. Chin J Osteoporosis 2021;27:1820-6 (in Chinese). Available from: https://kns.cnki.net/kcms2/article/abstract?v=lVku9qtM8H_PxItAvVTgZ0FQq7Ou0IRw43hh9WY78ncwGTSe-Hd8M6lclJPtvpkGoko0ayjPKpPevz7leKRiFItcdFbvVSLirlxVZV5pec8QJU33QANS2Fhz5n8RHuewPKqaA0TAGtv89YTufR2qpA==&uniplatform=NZKPT&language=CHS [Last accessed on 30 Nov 2023].

13. Yuan XM, Sun Y, Jia HW, Liu S, Zhao J, Xiong LZ. Metabomic study of GC-MS based Gu-Shu Dan on prevention of glucocorticoid-induced osteoporosis. Journal of Shenyang Pharmaceutical University 2021;38:1033-9.

14. Xu XX. Pharmacodynamics and metabolomics of cistanche deserticola and its active components against osteoporosis. Ningxia Medical University; 2018 (in Chinese). Available from: https://kns.cnki.net/kcms2/article/abstract?v=lVku9qtM8H_IsPy1piezgCxzLhwg5x5FpLvjn0oCO8nbHRJ2OaJxDw8c02Yf_Q7FuTIZZmjZS3ElLz4k0JK_4MY7FsHNxObzR9ZOY-c7CthKl7n8GT54EMVx59-XAua2seROrNr9I6FkpR34wTTVGg==&uniplatform=NZKPT&language=CHS [Last accessed on 30 Nov 2023].

15. Zhang AH, Ma ZM, Sun H, et al. High-throughput metabolomics evaluate the efficacy of total lignans from acanthophanax senticosus stem against ovariectomized osteoporosis rat. Front Pharmacol 2019;10:553.

16. Ma YS, Hou ZJ, Li Y, Zheng BB, Wang JM, Wang WB. Unveiling the pharmacological mechanisms of eleutheroside E against postmenopausal osteoporosis through UPLC-Q/TOF-MS-based metabolomics. Front Pharmacol 2020;11:1316.

17. Si Z, Zhou S, Shen Z, Luan F. High-throughput metabolomics discovers metabolic biomarkers and pathways to evaluating the efficacy and exploring potential mechanisms of osthole against osteoporosis based on UPLC/Q-TOF-MS coupled with multivariate data analysis. Front Pharmacol 2020;11:741.