fig4

Figure 4. Testosterone negatively modulates the expression of adiposity biomarkers. The exposure of adipocytes to testosterone (T) reduced the gene expression of FABP-4, PPARγ, leptin and adiponectin, while the co-exposure with the antiandrogen flutamide (Fluta/T) antagonized its effects. A complete set of five experiments that were run in triplicate were performed on each subject. Data are expressed as means ± DS. *P ≤ 0.05. FABP-4: Fatty acid binding protein 4; PPARγ: Peroxisome proliferation-activated receptor γ.