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From: The microbiome bone axis in osteomyelitis: integrating evidence from bone oral and gut microbiota
Figure 2. Microbiome-targeted interventions investigated in experimental models of osteomyelitis and related bone disorders. High-fat diet, Erxian Herbal Pair polysaccharide, oligofructose, and probiotic supplementation have been associated with distinct alterations in the gut microbiota and related inflammatory, metabolic, and bone outcomes. These interventions have been investigated across different experimental models and should not be considered equivalent or directly extrapolated to human osteomyelitis. Arrows indicate the reported direction of change. Created with BioRender. IL: Interleukin. Created in BioRender.
