fig5

Figure 5. Regulatory effects of GABA-producing Lactococcus lactis on central GABA signaling pathways. (A-G) mRNA expression levels of GABA receptor-related genes in the hippocampus: (A) GABRA11; (B) GABRA12; (C) GABRA13; (D) GABRA14; (E) GABRA15; (F) GABBR1; (G) GABBR2; (H) mRNA expression of the GABRA13 in the amygdala. (I) Protein expression of GABRA13 in the hippocampus; (J) GABA concentration in serum. Data were analyzed using one-way ANOVA followed by Dunnett’s multiple comparisons test against the MS group. ns stands for P > 0.05, *P < 0.05; **P < 0.01; ***P < 0.001. GABA: Gamma-aminobutyric acid; MS: model + stress.