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Figure 4. Characterization of the six primary bacterial pathogens associated with deaths due to AMR worldwide. (A) A heatmap illustrating the distribution and abundance of these six bacterial species in the upper respiratory tract of cats across various Chinese regions; (B) A heatmap displaying the distribution and abundance of these six bacterial species in the upper respiratory tract of cats in different living conditions; (C) Comparisons of the abundances of the bacteriome of these six bacterial species in the upper respiratory tract of cats from different Chinese regions; (D) Comparisons of the total abundances of the bacteriome of these six bacterial species in the upper respiratory tract of cats in different living conditions; (E) Comparisons of the abundances of the bacteriome of each of these six bacterial species in the upper respiratory tract of cats across different living conditions. Mann-Whitney U test was performed to compare the abundances between two groups, using pairwise multiple comparison adjustments according to the Benjamini-Hochberg procedure. The significance level was set at a P value of < 0.05 (*) and P > 0.05 is not marked. Different Chinese regions: NEC - Northeast China, NC - Northern China, EC - Eastern China, CC - Central China, SC - Southern China, NWC - Northwest China, SWC - Southwest China. Different living conditions: M - catteries, D - animal hospitals, L - stray bases. AMR: Antimicrobial resistance.