fig4

Pyridinic-N-Co single-atom catalysts unlock sustainable and efficient quinoline synthesis via hydrogen-transfer-coupled annulation

Figure 4. (A) Catalyst evaluation test, (B) the solvent effect, (C) the influence of temperature, and (D) the Co-N/C-U catalyst amount effect. Reaction conditions: 2-nitrobenzyl alcohol 1a (0.5 mmol), isopropanol 2a (1.1 mmol), solvent or THF (3 mL), catalyst (0.4 mol% metal or Co), N2, 80 °C, and 3 h. The yield and conversion are determined by GC using hexadecane as the internal standard.

Microstructures
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