fig5

Arginine metabolism disruption mediates 6-PPD quinone-induced mitochondrial toxicity at environmentally relevant concentrations in <i>Caenorhabditis elegans</i>

Figure 5. Effect of RNAi of aat-1, C50D2.2, slc-25A29, and argn-1 on 6-PPDQ toxicity in causing intestinal ROS generation (A), decreasing locomotion (B), and reducing brood size (C). Exposure concentration of 6-PPDQ was 10 μg/L. **P < 0.01. 6-PPDQ: N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone; aat-1: amino acid transporter 1; RNAi: RNA interference; slc-25a29: solute carrier family 25 member 29; ROS: reactive oxygen species.

Journal of Environmental Exposure Assessment
ISSN 2771-5949 (Online)

Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/

Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/