fig3

Figure 3. Effect of 6-PPDQ exposure on arginine catabolism. (A) Effect of 6-PPDQ exposure on expression of slc-25A29 and argn-1. ^**P < 0.01 vs. control; (B) Effect of RNAi of slc-25A29 and argn-1 on arginine content in 6-PPDQ-exposed nematodes. Exposure concentration of 6-PPDQ was 10 μg/L. ^**P < 0.01 vs. wild-type(L44440); (C) Effect of RNAi of aat-1 and C50D2.2 on expression of slc-25A29 and argn-1 in 6-PPDQ-exposed nematodes. Exposure concentration of 6-PPDQ was 10 μg/L. ^**P < 0.01 vs. wild-type(L44440). (D) Effect of RNAi of slc-25A29 on expression of argn-1 in 6-PPDQ-exposed nematodes. Exposure concentration of 6-PPDQ was 10 μg/L. ^**P < 0.01 vs. wild-type(L44440). 6-PPDQ: N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone; aat-1: amino acid transporter 1; RNAi: RNA interference; slc-25a29: solute carrier family 25 member 29.