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Figure 5. Exploratory histological and immunohistochemical findings in patients with available endomyocardial biopsy specimens. (A) representative hematoxylin-and-eosin-stained myocardial sections from IVIG-treated and non-IVIG-treated patients. (B) semiquantitative histological inflammatory scores. (C) representative immunohistochemical staining for myeloperoxidase (MPO), CD68, CD3, and CD20. (D) densities of MPO-positive neutrophils, CD68-positive macrophages, CD3-positive T cells, and CD20-positive B cells. Quantitative analyses included 6 IVIG-treated and 5 non-IVIG-treated patients, and each point represents one patient. Tissue acquisition was clinically indicated; the analysis was exploratory. Scale bar = 100 μm. Comparisons used the Mann-Whitney U test. *P < 0.05, **P < 0.01; ns: not significant.