fig5

Figure 5. Cardiomyocyte hypertrophy does not originate from the DNA released by cGAMP-induced macrophage death. (A) Schematic diagram of DNase I treatment in a co-culture system (generated by Figdraw, ID: OITPS2a3a3); (B) Protein levels of ANP and BNP in HL-1 cells co-cultured with Sting^{N153S floxed} and Sting^{LysM N153S} BMDMs; (C) Protein levels of ANP and BNP in HL-1 cells co-cultured with cGAMP-stimulated BMDMs. BMDMs: Bone marrow-derived macrophages; ANP: atrial natriuretic peptide; BNP: B-type natriuretic peptide; cGAMP: cyclic GMP-AMP.