fig1

Figure 1. Characterization of tetraspanin profile in sEVs. sEVs were isolated from (A) follicular fluid (n = 3), revealing a distinct feature where the CD9+ population is the least abundant; (B) peritoneal fluid of endometriosis patients (n = 7) and controls (n = 7). The tetraspanin profile in sEVs derived from endometriosis patients was similar to that of controls; specifically, CD81+ and CD9+ populations were more prevalent, whereas the CD63+ population was less abundant. Bars indicate mean ± 1 standard deviation; dots and squares represent individual samples. Data comparisons were performed between indicated groups using the non-parametric Mann-Whitney U tests. No multiple-comparison correction was applied. ^***P < 0.001 after Mann-Whitney U test. sEVs: Small extracellular vesicles.