fig6

5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer

Figure 6. Correlation Analysis of DhMGs with Clinical Indicators. (A) Heatmap of the correlation between different DhMGs and clinical indicators (OLGA and OLGIM); (B) Scatter plots showing the relationships between clinical indicators (OLGA, OLGIM) and the gene expression of DhMGs (NCOR2 and MEGF6) with clinical variables. The y-axis shows the normalized counts of DhMGs per sample, and the x-axis shows the OLGA or OLGIM score. *P < 0.05; **P < 0.01; ***P < 0.001. ns: Not significant (Pearson correlation coefficient test). OLGA: Operative link on gastritis assessment; OLGIM: operative link on gastric intestinal metaplasia assessment; DhMGs: differentially hydroxymethylated genes.

Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
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