fig5

5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer

Figure 5. Construction and Validation of the PLGC Diagnostic Model. (A) Stacked bar chart of model prediction results in the training set; (B) ROC curve of the model in the training set; (C) Confusion matrix of the model in the training set; (D) Stacked bar chart of model prediction results in the test set; (E) ROC curve of the model in the test set; (F) Confusion matrix of the model in the test set; (G) Heatmap of DhMGs in the diagnostic model across train and test cohort samples. PLGC: Precancerous lesion of gastric cancer; ROC: receiver operating characteristic; AUC: area under the curve; CAG: chronic atrophic gastritis; IM: intestinal metaplasia; Dys: dysplasia; DhMGs: differentially hydroxymethylated genes.

Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
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