fig2

Figure 2. Exosome-based detection of low-abundance miRNAs with potential application in liquid biopsy and biomarker monitoring. This platform enables highly sensitive detection of low-abundance exosomal miRNAs and illustrates the potential application of exosome-based miRNA profiling in liquid biopsy and biomarker development. Adapted from Zhang et al.^[105], used under the CC BY 4.0 license. miRNAs: MicroRNAs; dPCR: digital polymerase chain reaction; EXO: exosome; gDNA: genomic DNA; STAT3: signal transducer and activator of transcription 3; mRNA: messenger RNA.