fig4
Figure 4. Schematic diagram for the construction of OXA@Exo-RD nanocomposite and their applications in reversing chemoresistance and anti-metastasis[155]. DSPE-PEG-cRGD: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-cyclic arginylglycylaspartic acid; hUMSCs: human umbilical cord mesenchymal stem cells; Exo-R: cRGD-modified exosomes; DSPE-PEG-DQA: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-dequalinium; Exo-RD: dequalinium-modified exosomes; OXA: oxaliplatin; OXA@Exo-RD: oxaliplatin-loaded dequalinium-modified exosomes; ATP: adenosine triphosphate; ROS: reactive oxygen species.
