fig8

Chronic in utero oxycodone exposure alters placental small EV proteome and fetal cardiomyopathy-linked pathways

Figure 8. (A) Disease-specific KEGG enrichment shows significant downregulation of proteins involved in hypertrophic and DCM; (B) GeneMANIA interaction network of five downregulated cardiomyopathy-related proteins (Atp2a2, Lmna, Tgfb3, Agt, and Sgce) reveals interactions with regulators of cardiac signaling, fibrosis, calcium handling, and vascular function. KEGG: Kyoto Encyclopedia of Genes and Genomes; DCM: dilated cardiomyopathy.

Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
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