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From: Comparative analysis of adipose-, bone marrow-, and amniotic membrane-derived MSC secretomes and EVs reveals shared and source-specific therapeutic signatures for osteoarthritis

Comparative analysis of adipose-, bone marrow-, and amniotic membrane-derived MSC secretomes and EVs reveals shared and source-specific therapeutic signatures for osteoarthritis

Figure 1. MSC immunophenotype. (A) Cytograms of markers tested for each MSC type of the study. A representative donor is shown; (B) Percentage of positive cells for both MSCs (CD73/90/105/146) and hemato-endothelial (CD31/45) markers (N = 3; ^*P ≤ 0.05, ^***P ≤ 0.001, ^****P ≤ 0.0001). After assessment of normality of data distribution by the Shapiro-Wilk test, statistical significance was determined using one-way ANOVA. Data presented in PowerPoint. MSC: Mesenchymal stromal cell; ASCs: adipose-derived mesenchymal stromal cells; BMSCs: bone marrow-derived mesenchymal stromal cells; hAMSCs: human amniotic mesenchymal stromal cells; FSC: forward scatter; SSC: side scatter; CD: cluster of differentiation; ANOVA: analysis of variance; ns: not significant.