fig3

Figure 3. Representative graph of the Cell Mito Stress assay performed using the Seahorse XF analyzer. In the bar charts, each point in the OCR time courses represents the average of three technical replicates. Basal respiration, maximal respiration, proton leakage, ATP production, spare respiratory capacity, and non-mitochondrial respiration are reported. The values are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. control or among the groups. EveR: Everolimus-resistant; SorR: sorafenib-resistant; OCR: oxygen consumption rates; SEM: standard error of the mean.