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Figure 5. ID1 expression is high in PDAC tissue compared to normal samples and correlates with worse disease survival. (A) The percent of tumor samples with an either high or medium expression of ID1 on immunohistochemistry (IHC) was rank-ordered. The mRNA expression of ID1 in normal tissue was rank-ordered in normal tissue samples from the GTEx RNA-seq dataset. Arrow points to PDAC and pancreas tissue. (B) Direct comparison of mRNA expression data from PDAC tumors in the TCGA and normal pancreatic tissue from GETx. *P < 0.05. (C) PDAC patients in the TCGA dataset were grouped based on mRNA expression of ID1 split on the median value. High ID1 tumor expression predicted worse disease-free survival, P = 0.009 HR = 2.2.