fig5
From: EGFR signaling promotes resistance to CHK1 inhibitor prexasertib in triple negative breast cancer

Figure 5. Erlotinib co-exposure with prexasertib reduced BAD phosphorylation. MDA-231 cells treated with vehicle, 20 nmol/L prexasertib, 10 µmol/L erlotinib, or both 20 nmol/L prexasertib and 10 µmol/L erlotinib at 48 and 72 h (A); MDA-468 cells treated with vehicle, 20 nmol/L prexasertib, 10 µmol/L erlotinib, or both 20 nmol/L prexasertib and 10 µmol/L erlotinib at 48 and 72 h (B)