fig6

Figure 6. T-cell clone dynamics as measured by the TCR Beta assay correlate with changes in the pp65-responsive CD8+ T-cell population as measured by flow cytometry. The fold change in clone frequency for the ASSSAxYxYT family of clones in response to CMV lysate challenge is plotted relative to the fold increase in % pp65-responsive CD8+ cells in response to CMV lysate challenge for all four donors. Blue dotted line: linear regression analysis. The coefficient of determination (R²) for the correlation is shown. TCR: T-Cell receptor; CMV: cytomegalovirus