fig11

Figure 11. Integrated Analysis of Proteomic and Metabolomic Profiles in Hepatic Tissues from Control, OXA, and OCordy Mouse Groups. (A) Protein-metabolite interaction network for arginine biosynthesis and bile secretion pathways (red edges: arginine biosynthesis; blue edges: bile secretion); (B) Box plots of relative abundances for key differential metabolites (e.g., oxoglutaric acid, citrulline) in OXA and OCordy groups. Significance is denoted by asterisks. (^*P < 0.05, ^**P < 0.01, ^***P < 0.001). OXA: Oxaliplatin; OCordy: Oxaliplatin plus cordycepin.