fig2

Figure 2. Examples of limitations, associated with each therapeutic approach, contributing to treatment unfeasibility in HCC across the four dimensions: Technical Feasibility, Resources, Equity, and Values and Acceptability. Unfeasibility, indicated by the arrow, progressively increases with the curative potential of the treatment, such as in liver resection and transplantation. This image was created by the authors with Canva. HCC: Hepatocellular carcinoma; LT: Liver transplantation; LR: liver resection; LA: local ablation; IAT: intra-arterial therapies; ST: systemic therapies; HPB: hepatopancreatobiliary; PVT: portal vein thrombosis; DCD: donation after circulatory death; LDLT: living donor liver transplantation; GI: gastrointestinal.