fig1

Figure 1. The concept of “multiparametric therapeutic hierarchy” is based on three main pillars: (a) the ordinal therapeutic hierarchy (left vertical axis); (b) the multiparametric multidisciplinary expert decision (horizontal axis); (c) the converse therapeutic hierarchy (right axis). Adapted from Ref.^[14]. © 2023 Elsevier. Reprinted/adapted with permission from Elsevier. All rights reserved. PS: Performance status; AFP: alpha-fetoprotein; SD: stable disease; PD: progressive disease; LDLT: living donor liver transplantation; DCD: donation after circulatory death; WT: waiting time; CRPH: clinically relevant portal hypertension; MELD: Model for End-stage Liver Disease; TACE: transarterial chemoembolisation; PVT: portal vein thrombosis.