Volume 3 (2016) – 56 articles

Cover Picture: Toll-like receptors (TLRs) are part of the innate immune system and can initiate an immune response upon exposure to harmful microorganisms. Neuronal TLRs are considered to be part of an established framework of interactions between the immune system and the nervous system, the major sensing systems in mammals. TLRs in the nervous system and neuronal TLRs are suspected to be important during inflammation and neurodegenerative diseases. The aim of this review is to offer an overview of the current knowledge about TLRs in neurodegenerative pathologies, with a focus on Parkinson's disease. More research focusing on the role of TLRs in health and disease of the nervous system is needed and remains to be explored.

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Editorial

Astrocyte, reactive astrocytes and self-regulative apoptosis in the neuroinflammation

Liang-Wei Chen

Neurosciences 2016;3:167-9. DOI: 10.20517/2347-8659.2016.31

Editorial | Published on: 19 Jul 2016

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Serum immuno-biomarkers in gliomas

Robin A. Buerki, Rimas V. Lukas

Neurosciences 2016;3:198-200. DOI: 10.20517/2347-8659.2016.41

Editorial | Published on: 25 Sep 2016

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Interleukin-1beta: a common thread between inflammation, pain and opioid tolerance

Shekher Mohan

Neurosciences 2016;3:201-3. DOI: 10.20517/2347-8659.2016.37

Editorial | Published on: 25 Sep 2016

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Emerging roles of microglia cells in the regulation of adult neural stem cells

Eduardo Lira-Diaz, Oscar Gonzalez-Perez

Neurosciences 2016;3:204-6. DOI: 10.20517/2347-8659.2016.32

Editorial | Published on: 25 Sep 2016

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Schizophrenia and comorbid sleep disorders

Maurits van den Noort, ... Peggy Bosch

Neurosciences 2016;3:225-7. DOI: 10.20517/2347-8659.2016.42

Editorial | Published on: 27 Oct 2016

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Endocannabinoid metabolism in neurodegenerative diseases

Chu Chen

Neurosciences 2016;3:268-70. DOI: 10.20517/2347-8659.2016.46

Editorial | Published on: 14 Dec 2016

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On the need to unify neuroscience and physics

Maurits van den Noort, ... Peggy Bosch

Neurosciences 2016;3:271-3. DOI: 10.20517/2347-8659.2016.55

Editorial | Published on: 25 Dec 2016

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Review

The conflict on posttreatment Lyme disease syndrome: a clinical mini review

Manos Bogdos, ... Maria Kosmidou

Neurosciences 2016;3:10-3. DOI: 10.4103/2347-8659.171605

Review | Published on: 19 Jan 2016

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Neuro-oncogenesis and the adult human sub-ventricular zone in high grade glioma

Sara G. M. Piccirillo

Neurosciences 2016;3:20-6. DOI: 10.20517/2347-8659.2015.37

Review | Published on: 14 Feb 2016

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Neuronal toll-like receptors and neuro-immunity in Parkinson’s disease, Alzheimer’s disease and stroke

Carmen D. Rietdijk, ... Aletta D. Kraneveld

Neurosciences 2016;3:27-37. DOI: 10.20517/2347-8659.2015.28

Review | Published on: 14 Feb 2016

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Immunotherapeutic strategies for glioma treatment

George A. Alexiou, Athanassios P. Kyritsis

Neurosciences 2016;3:51-6. DOI: 10.20517/2347-8659.2015.45

Review | Published on: 13 Mar 2016

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Neurological diseases associated with autoantibodies targeting the voltage-gated potassium channel complex: immunobiology and clinical characteristics

Domenico Plantone, ... Tatiana Koudriavtseva

Neurosciences 2016;3:69-78. DOI: 10.4103/2347-8659.169883

Review | Published on: 27 Mar 2016

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Encephalitis associated with autoantibody binding to the anti-N-methyl-D-aspartate receptor: immunopathogenesis, mechanisms, and clinical characteristics

Adhasit Nawa-apisak, ... Metha Apiwattanakul

Neurosciences 2016;3:79-85. DOI: 10.4103/2347-8659.169913

Review | Published on: 27 Mar 2016

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Encephalitis associated with autoantibodies binding to γ-aminobutyric acid-A, γ-aminobutyric acid-B and glycine receptors: immunopathogenic mechanisms and clinical characteristics

Amy May Lin Quek, Orna O’Toole

Neurosciences 2016;3:86-92. DOI: 10.4103/2347-8659.170633

Review | Published on: 27 Mar 2016

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Diagnostic algorithms in autoimmune encephalitis

Valentina Damato

Neurosciences 2016;3:93-7. DOI: 10.20517/2347-8659.2015.43

Review | Published on: 18 Apr 2016

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Current and emerging therapies for neuromyelitis optica

Cong Zhao, ... Jun Guo

Neurosciences 2016;3:127-32. DOI: 10.20517/2347-8659.2016.11

Review | Published on: 19 Jun 2016

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Statins in acute neurologic disease: which one, which dose, when to start, and when not to stop

Bong-Su Kang, ... Nerses Sanossian

Neurosciences 2016;3:133-40. DOI: 10.20517/2347-8659.2015.27

Review | Published on: 19 Jun 2016

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Autoimmune encephalopathies in children: diagnostic clues and therapeutic challenges

Giorgia Olivieri, ... Eugenio Mercuri

Neurosciences 2016;3:147-55. DOI: 10.20517/2347-8659.2016.09

Review | Published on: 7 Jul 2016

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Necroptosis: a new link between cell death and inflammation

Yuan-Hang Pan, ... Ya-Zhou Wang

Neurosciences 2016;3:156-60. DOI: 10.20517/2347-8659.2015.59

Review | Published on: 7 Jul 2016

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Population of inflammatory cells in intracranial aneurysm with the special insight to the development of novel diagnostic and therapeutic approaches

Hirokazu Koseki, Tomohiro Aoki

Neurosciences 2016;3:173-9. DOI: 10.20517/2347-8659.2016.05

Review | Published on: 30 Aug 2016

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Immune-to-brain signaling and substrates of altered behavior during inflammation

Jan Pieter Konsman

Neurosciences 2016;3:207-14. DOI: 10.20517/2347-8659.2016.19

Review | Published on: 25 Sep 2016

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Neurological manifestations in Fabry disease

Joseph Bruno Bidin Brooks, Yara Dadalti Fragoso

Neurosciences 2016;3:228-31. DOI: 10.20517/2347-8659.2016.36

Review | Published on: 27 Oct 2016

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Original Article

Morphological and behavioural variation in CNS innate defence cell microglia is development and age sensitive

Payel Ghosh, Anirban Ghosh

Neurosciences 2016;3:38-47. DOI: 10.20517/2347-8659.2015.32

Original Article | Published on: 14 Feb 2016

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Assessment of health-related quality of life in patients with multiple sclerosis living in the Fars province of Iran

Nahid Ashjazadeh, ... Elham Farjam

Neurosciences 2016;3:57-62. DOI: 10.20517/2347-8659.2015.40

Original Article | Published on: 13 Mar 2016

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Thrombolysis lead to better long-term outcome in Chinese stroke patients

Nian-Tong Lin, ... Ping-Yi Xu

Neurosciences 2016;3:98-101. DOI: 10.20517/2347-8659.2015.46

Original Article | Published on: 18 Apr 2016

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Symptom severity, quality of sleep, and treatment adherence among patients suffering from schizophrenia and depression

Peggy Bosch, ... Jos Egger

Neurosciences 2016;3:109-16. DOI: 10.20517/2347-8659.2015.54

Original Article | Published on: 19 May 2016

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Inhibition and reversal of growth cone collapse in adult sensory neurons by enteric glia-induced neurotrophic factors

Simon Feng, ... Shu-Cui Jiang

Neurosciences 2016;3:180-8. DOI: 10.20517/2347-8659.2016.03

Original Article | Published on: 30 Aug 2016

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Possible role of microparticles in neuroimmune signaling of microglial cells

Stephanie M. Schindler, ... Andis Klegeris

Neurosciences 2016;3:232-42. DOI: 10.20517/2347-8659.2016.25

Original Article | Published on: 27 Oct 2016

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Current diagnosis and treatment of cryptococcal meningitis without acquired immunodeficiency syndrome

Xiao-Su Guo, ... Ze-Yan Zhao

Neurosciences 2016;3:249-56. DOI: 10.20517/2347-8659.2016.10

Original Article | Published on: 17 Nov 2016

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Low antioxidant status of patients with central nervous system infections

Jia Liu, ... Fu-Hua Peng

Neurosciences 2016;3:262-7. DOI: 10.20517/2347-8659.2016.20

Original Article | Published on: 14 Dec 2016

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Screening of genetic loci predisposing to herpes simplex virus infection on mouse chromosome 17

Xiu-Ying Chen, ... Wen Huang

Neurosciences 2016;3:274-82. DOI: 10.20517/2347-8659.2016.21

Original Article | Published on: 25 Dec 2016

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Guidelines

China guidelines for the diagnosis and treatment of myasthenia gravis

Zhu-Yi Li

Neurosciences 2016;3:1-9. DOI: 10.20517/2347-8659.2015.60

Guidelines | Published on: 19 Jan 2016

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Case Report

Artery of Percheron occlusion: role of diffusion-weighted imaging in the early diagnosis

Murali Krishna Menon, ... Muhammed Jasim Abdul Jalal

Neurosciences 2016;3:14-6. DOI: 10.4103/2347-8659.169916

Case Report | Published on: 19 Jan 2016

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Central nervous system blastomycosis presenting as a year-long chronic headache

Elena Grebenciucova, ... Rimas V. Lukas

Neurosciences 2016;3:17-9. DOI: 10.20517/2347-8659.2015.26

Case Report | Published on: 19 Jan 2016

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Infective endocarditis with brain lesions misdiagnosed as viral encephalitis

Jing-Jing Zhang, Guo-Dong Feng

Neurosciences 2016;3:48-50. DOI: 10.20517/2347-8659.2015.29

Case Report | Published on: 14 Feb 2016

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Bilateral facial weakness following dengue fever

Samir Patel, ... Pooja Gupta

Neurosciences 2016;3:63-4. DOI: 10.20517/2347-8659.2015.48

Case Report | Published on: 13 Mar 2016

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Disc herniation or ependymoma recurrence?

Aristeidis H. Katsanos, ... Athanassios P. Kyritsis

Neurosciences 2016;3:65-8. DOI: 10.20517/2347-8659.2015.42

Case Report | Published on: 13 Mar 2016

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Herpes zoster internuclear ophthalmoplegia

Vijayashankar Paramanandam, ... Gobinathan Shankar

Neurosciences 2016;3:102-3. DOI: 10.20517/2347-8659.2015.41

Case Report | Published on: 18 Apr 2016

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Spontaneous intracranial hypotension complicated with cerebral venous thrombosis and subdural effusion: a case report

Murali Krishna Menon, ... Muhammed Jasim Abdul Jalal

Neurosciences 2016;3:104-8. DOI: 10.20517/2347-8659.2015.35

Case Report | Published on: 18 Apr 2016

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A case of Hashimoto's encephalopathy presenting with seizures and cognitive impairment

Xing-Yong Chen, ... Xu Zhang

Neurosciences 2016;3:117-9. DOI: 10.20517/2347-8659.2015.57

Case Report | Published on: 19 May 2016

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Good recovery of a patient with neurocysticercosis using two antihelminthic drugs combined with steroid

Xin-Di Li, ... Xing-Hu Zhang

Neurosciences 2016;3:120-3. DOI: 10.20517/2347-8659.2015.51

Case Report | Published on: 19 May 2016

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Status epilepticus in scleromyxedema

Sofia Markoula, ... Athanassios P. Kyritsis

Neurosciences 2016;3:124-6. DOI: 10.20517/2347-8659.2015.39

Case Report | Published on: 19 May 2016

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Huge supratentorial cortical ependymoma in a young child: case report and literature review

Mehdi Darmoul, ... Mohamed Nejib Hattab

Neurosciences 2016;3:141-4. DOI: 10.20517/2347-8659.2015.53

Case Report | Published on: 19 Jun 2016

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Differentiation of radiation necrosis from glioblastoma recurrence after radiotherapy

Chrissa Sioka, ... Athanassios P. Kyritsis

Neurosciences 2016;3:161-4. DOI: 10.20517/2347-8659.2016.08

Case Report | Published on: 7 Jul 2016

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Progressive muscle cramps with pain as atypical initial presentations of amyotrophic lateral sclerosis: a case report

Cheng-Hui Liu, ... Yan-Jiang Wang

Neurosciences 2016;3:170-2. DOI: 10.20517/2347-8659.2015.49

Case Report | Published on: 19 Jul 2016

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D-cycloserin, a NMDA-agonist may be a treatment option for anti-NMDAR encephalitis

Hong-Zhi Guan, ... Li-Ying Cui

Neurosciences 2016;3:189-91. DOI: 10.20517/2347-8659.2016.29

Case Report | Published on: 30 Aug 2016

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Takayasu's arteritis - aphasia as an initial presentation

Davinder Singh Rana, ... Pooja Gupta

Neurosciences 2016;3:192-5. DOI: 10.20517/2347-8659.2015.52

Case Report | Published on: 30 Aug 2016

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A case report of acute pediatric bacterial meningitis due to the rare isolate, Pseudomonas putida

Grishma V. Kulkarni

Neurosciences 2016;3:215-8. DOI: 10.20517/2347-8659.2015.55

Case Report | Published on: 25 Sep 2016

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The expanding spectrum of pediatric anti-glutamic acid decarboxylase antibody mediated CNS disease - a chance association?

Deepak Menon, ... Sanjeev Thomas

Neurosciences 2016;3:219-24. DOI: 10.20517/2347-8659.2016.02

Case Report | Published on: 27 Sep 2016

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Cerebral venous thrombosis in patient of relapse of ulcerative colitis: report of a case

Rajat Agarwal, ... Samir Patel

Neurosciences 2016;3:243-6. DOI: 10.20517/2347-8659.2016.15

Case Report | Published on: 27 Oct 2016

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A case of anti-NMDA receptor encephalitis with ADEM-like clinical/MR findings

Jia Liu, ... Fu-Hua Peng

Neurosciences 2016;3:257-9. DOI: 10.20517/2347-8659.2016.28

Case Report | Published on: 17 Nov 2016

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Commentary

Meningeal inflammation and multiple sclerosis

Li-Ping Liu

Neurosciences 2016;3:145-6. DOI: 10.20517/2347-8659.2016.22

Commentary | Published on: 19 Jun 2016

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Sex differences in Alzheimer's disease

Yi Xing

Neurosciences 2016;3:165-6. DOI: 10.20517/2347-8659.2016.27

Commentary | Published on: 7 Jul 2016

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Auto-reactive B cells in MuSK myasthenia gravis

Yoon-Ho Hong, Jung-Joon Sung

Neurosciences 2016;3:196-7. DOI: 10.20517/2347-8659.2016.33

Commentary | Published on: 30 Aug 2016

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Comments on "Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression"

Jiu Chen

Neurosciences 2016;3:247-8. DOI: 10.20517/2347-8659.2016.30

Commentary | Published on: 27 Oct 2016

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Letter to Editor

Isolated unilateral chorea: a diagnostic challenge

Marta Lopes, Eva Brandão

Neurosciences 2016;3:260-1. DOI: 10.20517/2347-8659.2016.45

Letter to Editor | Published on: 17 Nov 2016

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